Prognosis of untreated wet AMD
Most people in the UK who are diagnosed with wet AMD will be eligible for and will likely be offered treatment for this condition. This was not, however, always the case. Before the advent of ‘anti-vegf injection treatments’ in particular, many people could not benefit from the treatments that were available.
Looking even further back into recent medical history we can devlve back into some of the early clinical trials that first investigated the potential impact of simple argon laser treatment for wet AMD. The data from these trials suggests that the prospect for an eye with a diagnosis of wet AMD to experience a severe degree of eyesight loss varies considerably with respect to the type of wet AMD identified.
The definition of severe eyesight loss was ‘losing six lines of vision on a standard eye test chart’.
The prospect of experiencing ‘severe sight loss’ in these studies varied from just under 30% for the slightly less aggressive ‘occult wet AMD’ up-to 60% or more for the more aggressive ‘classic wet AMD – over a two year time frame.
Therefore the risk of severe sight loss occurring in an UNTREATED eye with wet AMD is really quite considerable at between 30-60% over a two year time frame.
Needless to say with modern treatments it is possible to very significantly reduce this risk as we show in the next section.